Compound reference
CJC-1295
Also referenced as: DAC:GRF, Modified GRF 1-29
CJC-1295 reference material, with and without DAC: chemical structure, published receptor-binding research, purity/identity testing methodology, and storage specifications.
Identity and class
Synthetic growth-hormone-releasing hormone (GHRH) analog
A modified 29-amino-acid GHRH fragment analog; some preparations incorporate a Drug Affinity Complex (DAC) modification intended to extend plasma half-life via albumin binding.
Molecular formula (without DAC) C152H252N44O42; molecular weight approximately 3367.9 g/mol.
Published research areas
The subject matter of published laboratory literature. Listed as what was studied — not as an effect, and not as a use in humans.
- Laboratory studies have examined GHRH-receptor-analog binding kinetics in receptor-binding assay models.
- Published pharmacokinetic research has examined the albumin-binding behavior of DAC-modified GHRH analogs.
Handling and storage
- Supplied as a lyophilized powder.
- Manufacturer-recommended storage: -20°C for long-term storage, protected from light.
Citations
- GHRH analog tesamorelin: pharmacology and preclinical profile
Expert Opinion on Investigational Drugs · 2010