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Compound reference

GHK-Cu

Also referenced as: Copper Tripeptide-1, Glycyl-L-Histidyl-L-Lysine copper complex

GHK-Cu copper tripeptide complex reference material: chemical structure, published dermal and cellular research, HPLC/mass-spec verification, and storage guidance.

Identity and class

Copper-binding tripeptide complex

A tripeptide (Gly-His-Lys) complexed with a copper (II) ion, first isolated from human plasma.

Molecular formula C14H24CuN6O4; molecular weight approximately 403.9 g/mol for the copper complex.

Published research areas

The subject matter of published laboratory literature. Listed as what was studied — not as an effect, and not as a use in humans.

  • Published reviews have examined GHK-Cu's interaction with multiple cell-signaling pathways in cultured dermal fibroblast models.
  • Laboratory studies have examined copper-tripeptide complexes in extracellular matrix protein expression assays in vitro.
  • Research has examined GHK-Cu in gene expression profiling studies using cultured human cell lines.

Handling and storage

  • Supplied as a lyophilized powder; copper complexation gives the material a characteristic pale blue-to-teal color.
  • Manufacturer-recommended storage: -20°C for long-term storage, protected from light and moisture.

See how lyophilized material should be stored.

Citations