Compound reference
IGF-1 LR3
Also referenced as: Long R3 IGF-1
IGF-1 LR3 (Long R3 IGF-1) reference material: recombinant analog structure, published cell-proliferation research, purity and identity testing, and cold-chain storage.
Identity and class
Recombinant insulin-like growth factor 1 analog
A 83-amino-acid analog of human IGF-1 with an extended N-terminal sequence (13 additional amino acids) and an Arg3 substitution, reducing binding affinity to IGF binding proteins relative to native IGF-1.
Molecular weight approximately 9200 Da.
Published research areas
The subject matter of published laboratory literature. Listed as what was studied — not as an effect, and not as a use in humans.
- Published cell-culture research has examined IGF-1 receptor binding and downstream signaling in myoblast and fibroblast cell-line models.
- Laboratory studies have examined the reduced IGF-binding-protein affinity of the LR3 analog relative to native IGF-1 in vitro.
Handling and storage
- Supplied as a lyophilized powder.
- Manufacturer-recommended storage: -20°C, protected from light; recombinant protein material is sensitive to freeze-thaw cycling.
Citations
- Long R3 IGF-I and other analogs as tools for IGF receptor research
Growth Factors · 1996